Chitosan Nanoparticles Potentiate the in vitro and in vivo Effects of Curcumin and other Natural Compounds

The development of biodegradable nanoparticles is an important tool for the biological transport chemical compounds. nanoencapsulation reduces biopharmaceutical and pharmacokinetic drawbacks compounds enhances their properties. Naturally occurring polymers such as proteins polysaccharides have been widely applied in nanostructured systems several therapeutic agents. Among them chitosan, a crustacean-carapace-chitin derived biopolymer. In addition to its biocompatibility biodegradability, chitosan known mucoadhesion Chitosan-based potentiate most aspects loaded drugs, including cellular other effects. use permeation, stability, bioactivity natural this review, overview main features that improved vitro vivo effects bioactive molecules given, emphasizing results obtained with curcumin.